Renal function · AdultSource packet ready
CKD-EPI 2021 eGFR
2021 CKD-EPI creatinine equation without a race coefficient, indexed to 1.73 m² body surface area.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 2
Evidence ledger · Public by default
See the method behind every tool.
This ledger keeps source selection, calculation or decision-rule logic, automated checks, intended population, limitations, and version history visible in one place.
Sources attached Tests documented Restricted clinical scope
Current tool records
Last ledger update: July 17, 2026Risk & severity · Atrial fibrillationRestricted release
CHA₂DS₂-VASc
Additive 0–9 point factor score: CHF 1, hypertension 1, age 65–74 1 or ≥75 2, diabetes 1, stroke/TIA/thromboembolism 2, vascular disease 1, female sex category 1.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 2
Risk & severity · Atrial fibrillationRestricted release
HAS-BLED
Additive 0–9 point bleeding-risk factor score with renal and liver dysfunction, drug exposure, and alcohol counted separately.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 2
Risk & severity · Emergency medicineRestricted release
Wells Score for Pulmonary Embolism
Seven-item Wells PE score with the two-tier threshold: PE unlikely ≤4; PE likely >4.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 2
Risk & severity · PneumoniaRestricted release
CURB-65
One point each for confusion, urea >7 mmol/L, respiratory rate ≥30/min, low blood pressure, and age ≥65.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 2
Risk & severity · Suspected infectionRestricted release
qSOFA
One point each for respiratory rate ≥22/min, systolic blood pressure ≤100 mm Hg, and altered mentation.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 3
Risk & severity · Chest painRestricted release
HEART Score
Five 0–2 point domains: history, ECG, age, atherosclerotic risk factors, and troponin relative to the assay reference limit; total range 0–10.
- Version
- 0.1
- Updated
- July 21, 2026
- Automated tests
- Included
- Sources
- 2
Risk & severity · Pulmonary embolismRestricted release
PERC Rule
Eight binary criteria: age ≥50, pulse ≥100/min, oxygen saturation <95%, unilateral leg swelling, hemoptysis, recent surgery/trauma, prior VTE, and exogenous hormone use.
- Version
- 0.1
- Updated
- July 21, 2026
- Automated tests
- Included
- Sources
- 2
Risk & severity · Neurologic assessmentSource packet ready
Glasgow Coma Scale
Best eye response (1–4) + verbal response (1–5) + motor response (1–6); total range 3–15 with component notation retained.
- Version
- 0.1
- Updated
- July 21, 2026
- Automated tests
- Included
- Sources
- 2
Risk & severity · Critical careRestricted release
Sequential Organ Failure Assessment
Six organ-system subscores (respiratory, coagulation, hepatic, cardiovascular, neurologic, renal), each 0–4; total range 0–24.
- Version
- 0.1
- Updated
- July 21, 2026
- Automated tests
- Included
- Sources
- 2
Risk & severity · HepatologyRestricted release
Child-Pugh Score
Five 1–3 point domains: bilirubin, albumin, PT prolongation/INR, ascites, and encephalopathy; class A 5–6, B 7–9, C 10–15.
- Version
- 0.1
- Updated
- July 21, 2026
- Automated tests
- Included
- Sources
- 2
Renal function · AdultSource packet ready
Creatinine Clearance
Cockcroft–Gault (1976), with actual, Devine ideal, and adjusted body weight 0.4 shown separately.
- Version
- 0.2
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 4
Electrolytes · HyperglycemiaSource packet ready
Corrected Sodium in Hyperglycemia
Measured sodium + correction factor × ((glucose − 100) / 100), comparing Katz 1.6 and Hillier 2.4 mEq/L per 100 mg/dL.
- Version
- 0.2
- Updated
- July 21, 2026
- Automated tests
- Included
- Sources
- 2
Body size · Dosing supportSource packet ready
Body Surface Area
Mosteller, Du Bois & Du Bois, and Haycock equations displayed side by side.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 4
Body size · AdultSource packet ready
Body Size & Dosing Weight
Devine ideal body weight, adjusted body weight using a 0.4 correction factor, and BMI displayed separately.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 3
Electrolytes · Restricted estimateRestricted release
Corrected Calcium
Common simplified Payne-derived adjustment: total Ca + 0.8 × (4 − albumin g/dL), or SI equivalent +0.02 × (40 − albumin g/L).
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 3
Cardiology · ECG interpretationSource packet ready
QTc Comparison
Bazett, Fridericia, Framingham, and Hodges corrections displayed together; RR is derived as 60/heart rate.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 3
Acid–base · Laboratory interpretationSource packet ready
Anion Gap
Na − (Cl + HCO3), optional K inclusion, and optional albumin correction AG + 2.5 × (4 − albumin g/dL).
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 2
Toxicology · Laboratory interpretationSource packet ready
Serum Osmolality & Gap
2Na + glucose/18 + BUN/2.8, optional measured gap, and optional ethanol contributions using divisors 4.6 and 3.7.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 2
Hematology · Differential countSource packet ready
Absolute Neutrophil Count
ANC = WBC (cells/µL) × (segmented neutrophils % + bands %) / 100.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 1
Pharmacokinetics · GeneralSource packet ready
Two-Level Elimination
k = ln(C1/C2)/(t2−t1); half-life = ln(2)/k; optional first-order forward projection from the second level.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 2
Pharmacokinetics · Steady stateSource packet ready
Intermittent Infusion PK
Two-level first-order elimination plus steady-state intermittent-infusion equations for Cmax, Cmin, Vd, CL, AUCτ, AUC24, and accumulation.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 3
Vancomycin · Restricted first-order modelRestricted release
Vancomycin Two-Level AUC
Steady-state one-compartment intermittent-infusion model using two post-distribution levels; AUC24 = (dose/CL) × (24/interval).
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 3
Aminoglycosides · Restricted traditional dosing modelRestricted release
Gentamicin & Tobramycin Patient-Specific PK
Steady-state two-level Sawchuk–Zaske-style one-compartment workup with optional user-entered regimen simulation using patient-specific k and Vd.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 4
Aminoglycosides · Restricted traditional dosing modelRestricted release
Amikacin Patient-Specific PK
Steady-state two-level Sawchuk–Zaske-style one-compartment workup with optional user-entered amikacin regimen simulation using patient-specific k and Vd.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 4
Vancomycin · Restricted population projectionRestricted release
Initial Vancomycin Level Prediction
Matzke population k = 0.00083 × CrCl + 0.0044, editable Vd coefficient × weight, and finite-infusion first-dose and steady-state one-compartment projections.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 4
Aminoglycosides · Restricted protocol calculatorRestricted release
Extended-Interval Aminoglycoside Initial Regimen
Drug-specific high-dose protocol: gentamicin/tobramycin 7 mg/kg or amikacin 15 mg/kg using actual weight unless actual weight exceeds 120% of IBW, then AdjBW = IBW + 0.4(ABW−IBW); initial interval selected from protocol CrCl bands.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 4
Aminoglycosides · Restricted nomogramRestricted release
Hartford Random-Level Interval Assessment
One random concentration 6–14 hours after infusion start is plotted against a linear digitization of the published Hartford figure. Gentamicin/tobramycin require 7 mg/kg; the separately labeled amikacin adaptation uses 15 mg/kg and plots measured concentration ÷ 2. A ±0.2 mg/L line margin selects the longer interval.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 4
Infusion safety · Restricted point-of-care referenceRestricted release
Extravasation Intervention Chart
Searchable evidence synthesis mapping grouped drugs to warm, cold, either, or unspecified compresses and to agent-specific antidotes or interventions. No antidote preparation or dosing is generated.
- Version
- 0.1
- Updated
- July 17, 2026
- Automated tests
- Included
- Sources
- 5
Antimicrobial stewardship · Restricted point-of-care referenceRestricted release
Beta-lactam Cross-Sensitivity Reference
Reaction-phenotype triage plus a simplified R1 side-chain relationship map. Cross-reactivity estimates are shown only with the allergy-verification and structural-similarity populations from which they were derived.
- Version
- 0.2
- Updated
- July 21, 2026
- Automated tests
- Included
- Sources
- 4
Infusion safety · Restricted point-of-care referenceRestricted release
IV Medication Compatibility with Lactated Ringer's
Searchable synthesis separating simulated Y-site physical compatibility from manufacturer-supported use of LR as an infusion diluent, with formulation, concentration, contact-time, and age exceptions shown in the result row.
- Version
- 0.3
- Updated
- July 21, 2026
- Automated tests
- Included
- Sources
- 11
Publication standard
How a tool earns a place in RxTray
- 01Source assembly
Original equation, current guidance, validation studies, intended population, exclusions, units, and known controversies are recorded.
- 02Calculation check
Reference cases and boundary conditions are checked against the cited equations or decision rules.
- 03Clinical scope
Wording, applicability, limitations, units, and high-risk misuse cases are kept beside the tool.
- 04Versioned release
The evidence version, calculation version, update date, and material changes stay linked.
Restricted release · Evidence remains visible
Corrected calcium is available only after an explicit warning.
Generic albumin adjustment can misclassify calcium status, so the calculator resets to a locked state on every visit, prioritizes ionized calcium when accuracy matters, and never labels its output as a measurement.
Restricted clinical scopeMandatory evidence acknowledgementJuly 17, 2026
Historical equation · Primary publicationPayne et al. Interpretation of serum calcium in patients with abnormal serum proteins.Br Med J. 1973;4(5893):643–646. PMID: 4758544 ↗Contemporary population study · Validation studyDesgagnés et al. Use of albumin-adjusted calcium measurements in clinical practice.JAMA Netw Open. 2025;8:e2455251. PMID: 39836424 ↗Current position statement · GuidanceAlbumin-adjusted (‘corrected’) calcium should no longer be reported.Clin Chem Lab Med. 2026. PMID: 42035248 ↗
RxTray publishes source-backed clinical reference software with documented tests, versions, and limitations. No interface or evidence record should be treated as a substitute for professional judgment, current labeling, or institutional policy.