RxTrayClinical toolkit

Renal function · Adult

CKD-EPI 2021 eGFR

Estimate adult glomerular filtration rate with the 2021 creatinine equation, without a race coefficient.

Evidence recordSources and method currentVersion 0.1 · Updated July 17, 2026

Patient data

Enter current values

Private by design. Values are calculated on this device and are not saved or sent to analytics.

Result

Awaiting valid adult inputs

Age 18+ and creatinine required
mL/min/1.73 m²

The estimate will appear here.

A G category is not a CKD diagnosis. Chronicity, urine albumin, clinical context, and confirmatory testing matter. Drug labeling may require Cockcroft–Gault or non-indexed kidney function instead.

Evidence packet

What this tool is based on

This versioned record keeps the citations, equation or decision rule, units, test coverage, intended population, and exclusions attached to the tool.

How evidence review works →
Intended population

Adults age 18 years or older in whom a creatinine-based indexed eGFR is appropriate.

Equation record

2021 CKD-EPI creatinine equation without a race coefficient, indexed to 1.73 m² body surface area.

Unit handling

Serum creatinine accepts mg/dL or µmol/L using 88.4 µmol/L per mg/dL. Result is indexed mL/min/1.73 m².

Test coverage

Published-equation cases, sex coefficients, unit equivalence, adult-age boundary, G categories, and invalid inputs.

Do not skip

Limitations and exclusions

  • Not implemented for patients younger than 18 years.
  • Creatinine-based estimates are unreliable during rapidly changing kidney function and may be biased at muscle-mass extremes.
  • G category alone does not diagnose chronic kidney disease; chronicity and markers of kidney damage matter.
  • Medication labeling may require Cockcroft–Gault, measured clearance, cystatin C, or de-indexed kidney function instead.

About this tool

CKD-EPI 2021 eGFR Calculator

Use this eGFR calculator for the 2021 race-free CKD-EPI creatinine equation in adults. The result is indexed to 1.73 m² and the calculation record remains visible.

The calculator converts supported creatinine units before applying the published adult equation. eGFR and Cockcroft–Gault CrCl are different estimates and should not be substituted without checking the intended use.

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